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Toxicity evaluations demonstrate an IC50 above 300 g/mL for joint cells and no adverse effects in 28-day in vivo studies

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Research has also connected OPLAH to oxidative stress in cardiac tissue, underscoring that this is a pathway with real physiological weight

Last Published 01.01.2026 Effective Date: 01.01.2026 This policy addresses the use of devices to generate electric tumor treatment fields (TTF)