As GLP-1s can cross the blood-brain barrier and have a direct effect on brain function, it is important to examine their impact on mental health, especially in patients with mental illness. Researchers conducted a systematic review of studies assessing the impact of GLP-1s on mental health and metabolic outcomes in people with and without a mental illness between 2010 and August 2024
Many patients also find that specific supplements can enhance their results
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Structured behaviour change programmes: Services like Second Nature combine behavioural psychology with nutrition support, showing average weight losses of 6.2kg at 12 months in NHS trials