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doi: 10.1186/s12943-019-1068-1 249 WangZZhangHChengQ

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seven in absentia homolog 2 (SIAH2), a key regulator, together with hypoxia-inducible factor 1 alpha (HIF-1), of the cellular hypoxic responses under pathological conditions such as ischemia-reperfusion, whose association with NRF2 causes the degradation of NRF2 irrespective of its phosphorylation status [230]

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The result, presented at the American Heart Association (AHA) Scientific Sessions 2025 over the weekend, means that the CORALreef Lipids trial met its primary endpoint

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