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As a GLP-1 receptor agonist, semaglutide mimics a natural hormone in your body that regulates appetite, blood sugar, and digestion

C ssmin = (C -48h + C -24h + C 0h )/3

doi: 10.1007/s00210-024-03174-9 293 GongDWuNChenHZhangWYanCZhangCet al

This two-step binding process was thought to require the conformational flexibility and extensive surface contacts that only a peptide could provide