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Naringin was selected for the experiment based on the criteria such as whether its final metabolite of the pathway, specificity of the accumulation pattern, and cost-effectiveness

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Ludwig Kraus Key messages Table 1 The 30-day prevalence of the use of tobacco, electronic-inhalation and heat-not-burn products, and the use of water pipes (hookahs), as well as projections to the 18- to 64-year old population Table 2 The 30-day prevalence of alcohol use, as well as projections to the 18- to 64-year-old population Table 3 The 12-month prevalence of illegal drug use, as well as projections to the 18- to 64-year-old population Table 4 The 30-day prevalence of medicine use and daily use, as well as projections to the 18- to 64-year-old population Table 5 The 12-month prevalence of substance-related disorders according to DSM-IV, as well as projections to the 18- to 64-year-old population eFigure Course of data collection and response according to study arm eTable 1 Response according to study arm, n (%) eTable 2 A comparison of consumer variables according to type of survey method, n (%) *1 eTable 3 A comparison of variables of use according to willingness to participate, n (%)*1 The Use of Alcohol, Tobacco, Illegal Drugs and Medicines Info Specialities Citation manager

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