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Theres research behind this, mostly starting with animal work

Gomes CA, Junior CS, Di Saverio S, Sartelli M, Kelly MD, Gomes CC,

The data suggested that collagen type I synthesis, the predominant form of collagen in connective tissues, rose substantially under the influence of the peptide complex, in some cases reaching several times the baseline production level

GHK-Cu works through copper delivery to metalloenzymes and broad gene expression modulation, affecting not only collagen synthesis but also collagen cross-linking (via lysyl oxidase), glycosaminoglycan production, anti-inflammatory pathways, and antioxidant defense systems

lyophilized (unreconstituted) KLOW stored frozen has a substantially longer shelf life

However, it also suggests that GLP-1-based medication, which is administered in much higher doses, may be able to influence inflammation directly in the joints