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Clin Endocrinol (Oxf) 94(2):150157

10.2174/1381612826666200424180139 68 SikiriP.PetekM.RucmanR.SeiwerthS.GrabareviZ.RotkviI.et al (1993a)

Pickart and Margolinas 2018 review in Int J Mol Sci catalogs its regenerative and protective actions matrix remodeling, antioxidant and anti-inflammatory gene modulation, and wound-repair signaling but this is a review of largely preclinical and cell-based work (PMC6073405)

These include hypertension, diabetes, smoking, obesity, and a history of dyslipidemia

1: effects on mortality, pathology and sensory-motor performance in aging rats

The highest incidence of nausea and vomiting occurred during dose escalation phases