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In addition, it has been discovered that a metabolic shift toward fatty acid oxidation, necessary for tumor lymph node metastasis, occurs in tumor cells

Inhibition of recombinant endoplasmic reticulum resident protein 57 (ERp57) increases the protein defolding response and promotes the activation of PERK, which ultimately leads to increased levels of apoptosis in breast cancer cells [27]

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It binds to the growth hormone secretagogue receptor (GHS-R1a)